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Drug preparation for in vivo administration

FW Florence T.H. Wu
SM Shan Man
PX Ping Xu
AC Annabelle Chow
MP Marta Paez-Ribes
CL Christina R. Lee
SP Steven R. Pirie-Shepherd
UE Urban Emmenegger
RK Robert S. Kerbel
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Sunitinib malate (LC Laboratories) and its vehicle, formulated as previously described (5), were delivered by oral gavage (per os). Regorafenib monohydrate (Bayer HealthCare) was dissolved in a vehicle formulation containing 1,2-propanediol (34% w/v), PEG-400 (34% w/v), Kolliphor P188 (12% w/v), and Super-Q water (20% v/v) for per os administration. CVX-060/CVX-2000/ CVX-241 (Pfizer), DC101 (ImClone/Eli Lilly), and an antibody to mouse PD-L1 (clone 10F.9G2, BioXCell #BE0101) were diluted in PBS for intraperitoneal administration.

Copyright and License information:  ©2016-09-20

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