Data are presented as the mean ± SD. SPSS 20.0 (IBM Corp.) and GraphPad Prism 7.0 (GraphPad Software, Inc.) were used for data analysis. Student's t-test was used for statistical comparisons between two groups. One-way ANOVA was used for comparisons among multiple groups, followed by LSD or Bonferroni post hoc tests with equal variance and Dunnett's T3 with unequal variance. P<0.05 (or P<0.003 with Bonferroni correction) was considered to indicate a statistically significant difference.
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