Detailed information was extracted from each included study using a pre-structured data extraction form by two authors (M.S and N.A), separately. Any discrepancies between them were resolved through discussion; otherwise, they were resolved by the third author (R.H). Data on publication year, type of intervention (drug, screening, technology, surgery, vaccine, follow-up), year costs, sensitivity analysis (one way, two way, probabilistic sensitivity analysis and so on), perspectives adapted (society, health system, health insurance organization and so forth), discount rate, outcomes (ICUR or cost per QALY) and their recommendation were extracted. To standardize the results of studies conducted in different years, costs were deflated using the formula below:
n and r are year and inflation rate respectively.
In case an article did not report the year costs, year of the paper publication was considered as a base for cost adjustment. Moreover, in case an article used Rial for calculation, we converted Rial to USD to reduce heterogeneity.
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