A scatter plot was constructed to display the ΔTSS per year as a function of the adjusted MBDA score at the time of the first radiograph for all patients in the combined cohort. The percentage of patients with ΔTSS > 5 per year was determined for patient groups based on the category of adjusted MBDA score (low, moderate, or high) at the time of the first radiograph for each cohort and the four cohorts combined, without weighting. Rates of progression were also determined for subgroups within the high MBDA category.
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