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1) Acetone drop test

HC Huayong Chen
DM Dandan Ma
HZ Huapeng Zhang
YT Yanhong Tang
JW Jun Wang
RL Renhu Li
WW Wen Wen
YZ Yi Zhang
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The characteristic feature of neuropathic pain is the development of cold allodynia against non-painful (non-noxious) cold stimuli, including acetone. Using micropipette, acetone (100 μL) was applied (from below of the wired mesh) on the plantar surface of the hind paw. The duration for which the animal withdrew its paw was noted in seconds. This test was done three times with an interval of 5 minutes, and the cumulative paw withdrawal duration was noted [34].

Copyright and License information: The Korean Pain Society, ©2021
This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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