The daily dose of MMP is 1300 mg/day for humans. On the basis of weight/surface area, the conversion between human adult dose and mouse dose is a coefficient of 12.3. For the 1X MMP dose, the mouse dose used was 1300 (mg)/60 (kg) = 21.67, 21.67 × 12.3 (the conversion factor) = 270.6 mg/kg mouse dose.
Do you have any questions about this protocol?
Post your question to gather feedback from the community. We will also invite the authors of this article to respond.
Tips for asking effective questions
+ Description
Write a detailed description. Include all information that will help others answer your question including experimental processes, conditions, and relevant images.