The growth inhibitory effects of the test compounds against human skin fibroblast cells were measured by using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Compounds were dissolved in dimethyl sulfoxide (DMSO) and screened at a range of concentrations against normal cells. The cytotoxic activity was determined after 24 h. All experiments were repeated at least three times.
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