Mouse strains

Mice were maintained at the University of California, Berkeley. C57BL/6J, CD45.1-congenic (B6.SJL-Ptprc^a Pepc^b/BoyJ), Rag2^−/−, Rag2^−/− Il2rg^−/−, Ifnar1^−/− (all on the B6 background), and BALB/cJ mice were purchased from the Jackson Laboratory. Ncr1^iCre and Sting^gt/gt mice on the B6 background were gifts from E. Vivier and R. Vance, respectively. NK-DTA mice were generated by breeding Ncr1^iCre mice to B6-Rosa26^LSL-DTA mice (Jackson Laboratory). Ncr1^iCre/+, Ifnar1^fl/fl and CD11c-Cre, Ifnar1^fl/fl mice, all on the B6 background, were generated by breeding Ncr1^iCre and CD11c (Itgax)-Cre-eGFP (Jackson Laboratory) mice to Ifnar1^fl/fl mice (Jackson Laboratory). All mice used were aged 8 to 30 weeks. All experiments were approved by the University of California (UC) Berkeley Animal Care and Use Committee.