ROP screening and classification

HS Huiqing Sun
JS Juan Song
WK Wenqing Kang
YW Yong Wang
XS Xiantao Sun
CZ Chongchen Zhou
HX Hong Xiong
FX Falin Xu
ML Mingchao Li
XZ Xiaoli Zhang
ZY Zengyuan Yu
XP Xirui Peng
BL Bingbing Li
YX Yiran Xu
SX Shan Xing
XW Xiaoyang Wang
CZ Changlian Zhu
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ROP screening was performed for all very preterm infants (240/7–32) by qualified ophthalmologists with expertise, according to the Chinese guidelines for ROP screening [23]. Follow-up examinations were performed by the examining ophthalmologist based on retinal findings, classified according to the “International classification of retinopathy of prematurity revisited” [26, 27]. ROP was subdivided into stages 1–5 according to the classification and defined as follows [27]: (1) none: immature or mature vascularisation; (2) ROP: stage 1 or stage 2 ROP in zone II or III without plus disease; (3) type 1 ROP: zone I, any stage ROP with plus disease; zone I, stage 3 ROP without plus disease; zone II, stage 2 or 3 ROP with plus disease; (4) type 2 ROP: zone I, stage 1 or 2 ROP without plus disease or zone II, stage 3 ROP without plus disease; and (5) ROP requiring treatment was defined as type 1 ROP or worse. Termination of ROP screening was performed before 45 weeks postmenstrual age (PMA) [26].

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