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Drug Encapsulation and Loading Efficiency

ZL Zhen Liang
JL Juan Li
BZ Budong Zhu
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Drugs were isolated from the MLNPs were measured by redispersed the formulations in 0.1% Tween 80 and centrifuged (20,000 rpm, 15 min) and the supernatant was collected.35 The CIS content in MLNPs was determined by atomic absorption spectroscopy.13 The VNR and ATRA content were determined using HPLC at 269 nm and 340 nm.35,36 The drug encapsulation efficiency (EE) and loading efficiency (LE) of drugs loaded MLNPs were calculated by equations: EE (%) = The amount of drugs encapsulated in MLNPs/Total amount of drugs added×100%; LE (%) = The amount of drugs encapsulated in MLNPs/The amount of MLNPs×100%.

Copyright and License information:  ©2020 Liang et al.
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