4.2. Peptide Design and Synthesis

SEM18 (molecular weight: 2161.54 Da) and a random peptide (i.e., the CP, molecular weight: 2161.54 Da) was designed using the “dock proteins protocol” (ZDOCK, BIOVIA Discovery Studio 3.5; BIOVIA, San Diego, CA, USA), as previously reported [21]. SEM18 peptide and CP were then synthesized (Mission Biotech, Taipei, Taiwan) for experiments. The purity values of SEM18 peptide preparation and CP preparation were both 95%, as tested using high-performance liquid chromatography.