Dalton's Lymphoma Ascites (DLA) cells (1 × 106) were injected to the left thigh region of Swiss albino mice and tumor was induced16,27,30. Treatment was started once the tumor size was measurable. Two separate sets of experiments were conducted, with 14 continuous oral doses of 50 mg/kg body weight of Disarib to both male and female mice. The control group contained five animals and the treatment group had 12 animals. Tumor volume was measured as explained in Sect. "Breast adenocarcinoma tumor model".
Do you have any questions about this protocol?
Post your question to gather feedback from the community. We will also invite the authors of this article to respond.