The original strain SH1 was obtained from China’s edible fungi sub-center of microbial culture collection center. The mutant strain A130 were bred by automated ARTP mutation breeding system and screened. After the ARTP treatment and screening, the optimal strain A130 was identified with genetic stability in the submerged culture experiment.
Murine macrophage cell line RAW264.7 cells and human monocytic cell line THP-1 cells were purchased from the Type Culture Collection of the Chinese Academy of Sciences.
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