DM-Sham and DM + MCAO mice were used as controls. All results were presented as mean ± standard error of mean (SEM). All statistical analysis was carried out with SPSS v21.0 (SPSS Inc., Chicago, IL, United States) by one-way ANOVA followed by Two-tailed unpaired Student’s t-test. Dunnett’s test was used to compare many experimental treatments each to a single control following one-way ANOVA. A value of p < 0.05 was considered statistically significant.
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