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AL Aowei Lv
ZZ Zaiqiang Zhang
YF Ying Fu
YY Yaping Yan
LY Li Yang
WZ Wenli Zhu
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This was a prospective observational study. Patients were consecutively recruited from Tianjin Medical University General Hospital and Beijing Tiantan Hospital. Only patients with clinically manifested CSVD and at least one of the imaging features (lacuna, WMH, EPVS, and CMBs) were eligible to participate in this study. MS was diagnosed using 2017 McDonald criteria. Main exclusion criteria were patients with (1) unidentified vascular risk factors for CSVD such as a history of hypertension, hypercholesterolemia, diabetes mellitus (DM), smoking, and alcohol consumption; (2) evidence of other diseases that could potentially also cause WMLs; and (3) contraindications to MRI scanning.

Copyright and License information:  ©2020 Lv, Zhang, Fu, Yan, Yang and Zhu.
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