Siglecg−/− FA-AKI

AI Akimichi Inaba
ZT Zewen K. Tuong
AR Alexandra M. Riding
RM Rebeccah J. Mathews
JM Jack L. Martin
KS Kourosh Saeb-Parsy
MC Menna R. Clatworthy
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Four male WT BALB/c and seven male Siglecg−/− (Siglecgtm1Lnit, MGI:3718495) mice from two littermate sets between 16 and 18 wk old received half-dose FA-AKI (125 mg/kg FA). Extravascular kidney B cells were gated as single, live, in vitro CD45+, intravascular CD45, CD19+ events. Extravascular kidney neutrophils were gated as single in vitro CD45+, intravascular CD45, GR1+, CD11b+ events. Extravascular kidney monocytes were gated as single, live, in vitro CD45+, intravascular CD45, Ly-6ClowMHCIIhigh events.

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