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SOD1G93A mice were intragastrically administered rofecoxib (50 mg/kg/day) by gavage. In brief, a suitable gavage needle was selected and fixed on a 1 ml syringe. The mice were then prepared via alignment of the head, neck, and body. The gavage needle was introduced into the corner of the mouth, pressed against the tongue, pushed inwardly against the upper jaw, and ultimately introduced into the esophagus. The injection volume was usually controlled to 0.1–0.2 ml/10 g. The gavage needle was removed gently after the injection.
Copyright and License information: ©2020 Zou, Guan, Zhang, Guo and Wang.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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