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Immunogenicity of Lipid Nanostars After Intravenous Injection
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To evaluate the immunogenicity of all nanoparticles, LNSs and LNPs were intravenously injected into Balb/c mice at a dosage of 10 mg per mouse. After 24 h, the mice were anesthetized with isoflurane, and blood was collected and centrifuged at 3,000 rpm for 15 min after standing at room temperature for 15 min. The aspartate transaminase (AST), alanine transaminase (ALT), urea, and creatinine in the serum was analyzed by the Department of Biochemistry, Sun Yat-sen Memorial Hospital.
Copyright and License information: ©2020 Cao, Liu, Li, Lin, Zhang, Tan, Liang, Luo, Xu and Saw
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