DAS28-ESR scores (= [0.56 × √TJC] + [0.28 × √SJC] + 0.70 × ln[ESR] + 0.014 × PGA [in mm]), DAS28-CRP scores (= [0.56 ×√TJC] + [0.28 ×√SJC] + (0.36 × ln[CRP; in mg/l]) + 1) + (0.014 × PGA [in mm]) + 0.96) and SDAI ( = SJC + TJC + PGA [VAS; in cm] + EGA [VAS; in cm] + CRP [in mg/dL]) were calculated as previously described3,19. DAS28-MCP-1 score was calculated with the following modified DAS28 formula: DAS28-MCP-1 = 0.56 × √TJC + 0.28 × √SJC + 0.39 × ln(MCP-1; in pg/mL) + 0.014 × (PGA [in mm])17.
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