Imaging Protocol

All patients underwent ¹⁸F-rhPSMA-7 PET/CT on a Biograph mCT flow scanner (Siemens Medical Solutions). A diagnostic CT scan was performed in the portal venous phase 80 s after intravenous injection of contrast agent (Iomeron 300), followed by the PET scan. All patients received diluted oral contrast medium (300 mg of ioxitalamate [Telebrix; Guerbet]). All PET scans were acquired in 3-dimensional mode with an acquisition time of 1.1 mm/s. Emission data were corrected for randoms, dead time, scatter, and attenuation and were reconstructed iteratively by an ordered-subsets expectation maximization algorithm (4 iterations, 8 subsets) followed by a postreconstruction smoothing gaussian filter (5 mm in full width at half maximum).