Improve Research Reproducibility A Bio-protocol resource
Concise Method
tooltip

Annotation of TSGs and cancer-specific NMD signature

ZH Zhiyuan Hu
CY Christopher Yau
AA Ahmed Ashour Ahmed
request Request a Protocol
ask Ask a question
Favorite

The list of cancer-related genes and TSGs was downloaded from COSMIC (http://cancer.sanger.ac.uk/census)12. The number of studied TSGs is 71. The 127 SMGs were reported by pan-cancer mutation analysis11. We defined the top NMD-affected genes for each cancer as the genes harbouring NMD mutations within over 5% samples. We marketed genes that are potential false-positive cancer-associated genes, such as TTN and MUC16 (ref. 28; Table 1).

Copyright and License information:  ©2017, The Author(s)
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

Do you have any questions about this protocol?

Post your question to gather feedback from the community. We will also invite the authors of this article to respond.

0/150

tip Tips for asking effective questions

+ Description

Write a detailed description. Include all information that will help others answer your question including experimental processes, conditions, and relevant images.

post Post a Question
0 Q&A