Caerulein-Induced Acute Pancreatitis.

AW Amanda R. Wasylishen
CS Chang Sun
GC Gilda P. Chau
YQ Yuan Qi
XS Xiaoping Su
MK Michael P. Kim
JE Jeannelyn S. Estrella
GL Guillermina Lozano
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Acute pancreatitis was induced based on established protocols. Caerulein (MedChemExpress) was reconstituted in sterile PBS. Adult mice (6 to 10 wk old) were injected (individual dose: 75 μg/kg), given as eight hourly i.p. injections on 2 consecutive days during the light cycle. Mice were s.c. administered sustained release buprenorphine as an analgesic prior to the first caerulein injection.

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