The spreadability (n = 3) of AmB gel was determined by placing 0.5 g of the formulation between a plate and a millimeter glass plate cover. Different weights (2, 5, 10, 20, 50, 100, 200 and 300 g) were successively placed on top for 2 min each at RT. Spread diameters were measured and fitted into mathematical models using GraphPad Prism® version 6.0 (GraphPad Software Inc., San Diego, CA, USA).
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