Subjects.

Ten healthy, young men {mean [95% confidence interval (CI)]: 24 (22, 27) yr, 1.77 (175, 179) m, 78 (72, 85) kg} who previously participated in an investigation of a single bout of LL-RE and LL-BFR (43) consented to perform 6 wk of training. Before enrollment, participants completed the Physical Activity Readiness Questionnaire (PAR-Q⁺), were informed of the risks involved, and provided written informed consent. Inclusion criteria consisted of the absence of major injuries in the past 6 mo, the absence of musculoskeletal disease, no previous lower-body resistance training experience (≥1 day/wk) for ≥6 mo, and abstinence from a periodization program for ≥1 mo before study commencement. The study was reviewed and approved by the University of Guelph research ethics board (REB no. 17-12-005) in accordance with the Declaration of Helsinki.