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Assessing prostate-specific shRNA incorporation/depletion

PS Poppy Simmonds
EL Erick Loomis
EC Edward Curry
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Gene-level short hairpin (shRNA) selection biases in 216 cancer cell lines were downloaded from the Project Achilles portal (https://portals.broadinstitute.org/achilles). Prostate-specific lethality was tested by using a t test to compare the selection bias z-score in prostate cancer cell lines with the z-scores from all non-prostate cancer cell lines.

Copyright and License information: The Author(s). ©2017
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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