Drugs

Δ⁹-Tetrahydrocannabinol, ADBICA (N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H-indole-3-carboxamide), ADB-PINACA (N-[1-(aminocarbonyl)-2,2-dimethylpropyl]-1-pentyl-1H-indazole-3-carboxamide), THJ-2201 ((1-(5-fluoropentyl)-1H-indazol-3-yl)(naphthalen-1-yl)methanone), RCS-4 ((4-methoxyphenyl)(1-pentyl-1H-indol-3-yl)methanone), JWH-122 ((4-methyl-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)-methanone), JWH-210 ((4-ethyl-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)-methanone) were provided by the National Institute on Drug Abuse Drug Supply Program. All drugs were dissolved in ethanol/Cremophor EL/0.9% saline (1:1:18) and were administered i.p. in a volume of 1 ml/kg.