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Animal experiment was approved by the Animal Research Committee of Xuzhou Central Hospital. Tumor xenograft model was established using BALB/c nude mice by subcutaneously injecting 2 × 106 miR-663 or miR-NC transfected SKOV3 cells. Tumor volume was monitored once every 3 days by assess the tumor width and length. The formula of tumor volume is (length × width2)/2. After 25 days, tumor mass were exfoliated and weighed.
Copyright and License information: The Author(s) ©2019
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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