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To identify variants within the PTM motif, data were downloaded from Humsavar (The UniProt, 2017)5 and PTMvar (Hornbeck et al., 2015)6. The data were programmatically parsed using Perl script, and variants at PTM sites were mapped for the sirtuin interactors. As before, the variants were mapped onto the motif of ±7 amino acids around a PTM site. Any variant overlapping exactly at the site of modification or in vicinity (within the motif) around it was considered for further analysis.
Copyright and License information: ©2020 Aggarwal, Banerjee, Talukdar and Yadav.
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