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2.3. Connectivity Map (CMap) Analysis

GL Guangrong Lu
LC Liping Chen
SW Shengjie Wu
YF Yuao Feng
TL Tiesu Lin
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CMap (https://portals.broadinstitute.org/cmap/, RRID:SCR_015674) was used to find connections between drugs and genes [18]. Up tag file and down tag file were uploaded into the quick query of the tool web. The value of connectivity score fluctuated between -1 and 1, and a high negative connectivity score manifested that the drug reversed the expression of the query signature.

Copyright and License information:  ©2020 Guangrong Lu et al.
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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