To investigate the biodistribution of nanoparticles in vivo, xenograft-bearing mice were divided into four groups (n=3; NP, NP-DC, T7-NP-D, and T7–NP–DC). The Cy5.5-labeled nanoparticles were injected intravenously and then the fluorescence distribution in mice was observed at 2 and 8 hours using an in vivo live imaging instrument.
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