Hot plate assay

Chun-An Chen; Rituraj Pal; Jiani Yin; Huifang Tao; Abdallah Amawi; Aniko Sabo; Matthew N Bainbridge; Richard A Gibbs; Huda Y Zoghbi; Christian P Schaaf

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Hot plate assay

CC Chun-An Chen

RP Rituraj Pal

JY Jiani Yin

HT Huifang Tao

AA Abdallah Amawi

AS Aniko Sabo

MB Matthew N Bainbridge

RG Richard A Gibbs

HZ Huda Y Zoghbi

CS Christian P Schaaf

This method is extracted from research article: Hum Mol Genet, Jan 2020

Combination of whole exome sequencing and animal modeling identifies TMPRSS9 as a candidate gene for autism spectrum disorder

DOI: 10.1093/hmg/ddz305

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Hot plate assay was used to test the pain recognition in mice as previously described (24). The mice were placed on a 55°C hot plate (Columbus Instruments). The latency to hindlimb response (jumping, shaking, or licking) was manually recorded. Data are shown as mean ± standard error of mean and analyzed by one-way ANOVA with Bonferroni’s post hoc analysis.

This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

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