2.5. Synthesis of P(HEMA-co-MPEGMA) (Example for VIII)

In a Schlenk flask, MPEGMA (4.97 mL, 10.74 mmol), HEMA (3.92 mL, 32.23 mmol), dNbpy (98.65 mg, 0.241 mmol), 4nBREBr₂ (53.00 mg, 0.107 mmol), and solvents (0.89 mL, 10 vol % of monomers, methanol:anisole = 1:9 (v/v)) were mixed. Next, three freeze–pump–thaw cycles were applied to degas the reaction mixture, and a catalyst (CuBr, 15.39 mg, 0.107 mmol) was added. The reaction was then carried out at 60 °C (in an oil bath) and stopped by exposure to air. After dissolving the reaction mixture in chloroform, CuBr was removed by cationite (Dowex). The product was precipitated in heptan, isolated by decantation, and dried to constant mass.