All statistical analysis of the data in this study was done with SPSS version 24.0 (IBM Corporation, Armonk, NY, USA). Univariate and multivariate analyses were used in all patients to assess independent factors affecting OS and PFS. Differences between groups were assessed using independent sample t-test, chi-square test, Kaplan-Meier survival analysis, and log-rank test. A value of p<0.05 was considered to be statistically significant.
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