Fluorescence Imaging of Nanoparticles in Tumor-Bearing Mice Post-PDT

ZL Ziying Li
YY Yanxue Yin
WJ Weiwei Jin
BZ Bo Zhang
HY Han Yan
HM Heng Mei
HW Huafang Wang
TG Tao Guo
WS Wei Shi
YH Yu Hu
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Mice were injected with Dir-labelled nanoparticles, and PDT was delivered, as previously reported, for 15 min (20). At various points (3 h, 6 h, 10 h, 24 h) post-PDT, fluorescent scans (Ex/Em: 730/790 nm) were conducted on anesthetized mice using the Maestro 2 In Vivo Imaging System (CRI, USA). Mice were euthanized 24 h post-PDT, and tumors were harvested. Each tumor was washed with PBS and then subjected to fluorescence imaging.

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