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Calculations concerning APOBEC-Induced Mutational Clusters.
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Two different methods were used to determine whether APOBEC-induced mutations were clustered, one based on a Poisson analysis (the P-method) and using a negative binomial distribution (the B-method) (18). The details of these methods are in the text above and in SI Appendix.
Copyright and License information: ©2020 the Author(s). Published by PNAS.
This open access article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND).
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