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2.2. GO and KEGG Pathway Enrichment Analysis

SL Songyi Liu
HY Honghao Yin
SZ Shuwen Zheng
AC Aining Chu
YL Yizhi Li
CX Chengzhong Xing
YY Yuan Yuan
YG Yuehua Gong
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Gene Ontology (GO) analysis is the primary bioinformatics tool to unify the characterization of genes and gene products [22]. GO contains three categories of terms, including cellular component, molecular function, and biological process. KEGG is a set of databases containing information about genomes, biological pathways, diseases, and chemicals [23]. DAVID (https://david.ncifcrf.gov/) is a bioinformatics data resource with an integrative bioinformation database and analysis tools and benefits to discover the biological meaning behind genes [24]. DEGs were enriched and analyzed by DAVID for GO and KEGG pathways, respectively. P < 0.05 was considered statistically significant.

Copyright and License information:  ©2020 Songyi Liu et al.
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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