Healthy C57BL/6 mice (weight 18–20 g) and ICR mice (weight 18–22 g) were obtained from the Experimental Animal Center of SLac-kinda (Changsha, China), kept at 20–25 °C under a 12-h light/dark cycle, and fed with standard rodent chow and water ad libitum. All the experimental protocols were approved by the Animal Care and Use Committee (ACUC) at the Hunan Province Animal Management Office.
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