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2.3. APP Transgenic Mouse Model of Alzheimer’s Disease (AD)

CS Carlos A. Saura
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APPSw,Ind transgenic mice (line J9; C57BL/6 background), expressing human APP695 harboring the familial AD-linked Swedish (K670N/M671L) and Indiana (V717F) mutations under the PDGFβ promoter, were obtained by crossing APPSw,Ind to non-transgenic (WT) mice [20]. Animals come from a colony established by co-author Carlos A. Saura in the Autonomous Barcelona University; animals came directly from the laboratory who developed the transgenic animal after signing the ad hoc Transfer Agreement.

Copyright and License information:  ©2020 by the authors.
Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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