C. elegans strains

Strains of C. elegans were cultured and maintained using standard protocols (Brenner, 1974) unless indicated otherwise. The N2 Bristol strain was used as the wild type (WT) strain Genome-integrated arrays (qxIs) were acquired by γ-irradiation to achieve stable expression from arrays with low copy numbers. The following strains were used in this work: linkage group (LG) I, daf-16(mu86), hsf-1(sy441); LG II, eat-2(ad1116); LG III, daf-2(e1370ts), cup-5(bp510); LG IV, skn-1(zj15), isp-1(qm150), hlh-30(tm1978); LG V, cpl-1(qx304), hif-1(ia4). The reporter strains used in this study include qxIs257 (P_ced-1NUC-1::CHERRY), qxIs468 (P_myo-3LAAT-1::GFP), qxIs520 (P_vha-6LAAT-1::GFP), qxIs750 (P_hsNUC-1::pHTomato), qxIs612 (P_hsNUC-1::sfGFP::CHERRY), zuIs45 (P_nmy-2NMY-2::GFP).