Venous Thrombosis Mouse Models

VT was formed via (1) generation of stasis by inferior vena cava (IVC) ligation or (2) generation of stenosis via partial ligation of the IVC.²⁶ Following laparotomy, VT was induced by infrarenal IVC ligation with a single 7–0 prolene suture with concurrent cauterization of lumbar and side branches; or in the case of the stenosis model, a prolene was tied around a 30-gauge needle adjacent to the IVC to produce turbulent flow and stenosis with side branch ligation, but without lumbar branch cauterization.²⁶