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Glycosylation

CS Chadi M. Saad-Roy
NA Nimalan Arinaminpathy
NW Ned S. Wingreen
SL Simon A. Levin
JA Joshua M. Akey
BG Bryan T. Grenfell
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Under no immune selection, the probability of glycosylation at site i was calculated by finding the probability of having the Asn−X−Ser/Thr sequon [39] (where X is not proline) assuming site independence. This assumption is necessary and implicit as DMS data only consider single residue changes on a specific background HA protein. In particular, these data do not consider epistatic interactions between residues, including any such interactions that would enrich Asn−X−Ser/Thr sequons. Therefore, the estimate of the glycosylation probability at site i is

Copyright and License information:  ©2020 Saad-Roy et al
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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