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Homology modelling of SARS-CoV-2-S protein

BB Bharath BR
HD Hrishikesh Damle
SG Shiban Ganju
LD Latha Damle
RH Raghavendra HL
SV S.M. Vidya
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Homology modelling was performed with SWISS-MODEL for the protein sequence of SARS-CoV-2-S using the crystal structure of SARS-CoV-S and ACE2 complex (PDB ID: 6ACD) as a template. The modelled protein was validated for quality using a Ramachandran plot and prepared for molecular docking studies using the Protein Preparation Wizard feature of the Schrodinger Small Molecule Suite 31. This analysis could also have been performed using open source software such as AutoDock 32 or SwissDock 33.

Copyright and License information:  ©2020 BR B et al. : ©2020 HL RThis is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. : ©2020 Vidya SMThis is an open access peer review report distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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