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Cardiac hypertrophy in 8-week-old male C57BL/6N mice was induced by chronic infusion of angiotensin II (Sigma, 1.5 mg/kg/day) for a continuous 4 weeks as described previously (Tang et al., 2017). In brief, an Ang II-contained minipump (ALZET 2004) was placed into the mouse subcutaneously. Mice and SD rats were purchased from Charles River. The protocol for the animal study was approved by the ethics review boards at Jiamusi University.
Copyright and License information: ©2020 Yu, Li, Zhao, Wang and Chen.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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