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T1DM: this includes any subjects with established T1DM, according to the American Diabetes Association, without a honeymoon period and taking an insulin dose of >0.5 unit/kg/day.

Control: this includes any subject without T1DM and other diseases.

The subjects with T1DM were divided into two groups according to the duration of T1DM: a group with a duration of T1DM of fewer than 7 years and a group with >7 years.

The subjects with or without T1DM were divided into two groups according to their family history of T2DM within their first-degree relatives: a group with positive family history and a group with negative family history.

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