The Gene Expression Profiling Interactive Analysis (GEPIA) analysis

GEPIA, a web-based tool to deliver fast and customizable functionalities based on The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) project provide key interactive functions including differential expression analysis, profiling plotting, correlation analysis, and patient survival analysis (36). We investigated the differential expression and prognostic values of GPX genes in the “Single Gene Analysis” module of the GEPIA database (http://gepia.cancer-pku.cn/). Multiple gene comparison analysis of GPXs was conducted with the “Multiple Gene Comparison” module, using the “LAML” dataset. Student’s t-test was used to perform expression analysis. The survival results were displayed with hazard ratios (HRs) and P values from a log-rank test. The P value cutoff was 0.05.