2.3. Liver stiffness measurement

In clinical practice, the FibroScan tests were firstly recommended to evaluate liver fibrosis and cirrhosis in patients with CHB and NAFLD because of its noninvasive nature and relatively high diagnostic performance. Transient elastography examinations were performed by trained operators according to the manufacturers’ recommendations using the standard probe (M probe) 1 to 3 days before liver biopsy.^[18] The LSM values were considered reliable when 10 valid examinations were obtained with the maximum number of attempts set at 20. The FibroScan evaluation was considered as unreliable when IQR/LSM was >0.30 in patients with LSM ≥7.1 kPa.^[19]