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Open field test

WT Wiebke Theilmann
MR Marko Rosenholm
PH Philip Hampel
WL Wolfgang Löscher
TR Tomi Rantamäki
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The open field test is a routine method to measure locomotor activity and anxiety-like behavior in rodents [51]. The test was performed in a round arena made of black PVC (diameter 80 cm) which was divided into three zones (center, inner, outer). The animals were placed individually in the center of the open field. Distance moved and time spent in the center of the open field was recorded for 5 min and analyzed with EthoVision®XT7 software (Noldus Information Technology, Wagening, Netherlands).

Copyright and License information:  ©2020 Theilmann et al
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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