Previous study in our population, have indicated that the prevalence of allergen-specific IgE (sIgE) for the studied aeroallergens was greater than the skin prick test (SPT) positivity, and the frequency of SPT positivity between those without sIgE was very low [56]. For this reason, atopy was defined as the presence of at least one positive test for a relevant aeroallergen with sIgE ≥ 0.70 kU/L. The sIgE was determined by ImmunoCap using caps to Blomia tropicalis, Dermatophagoides pteronyssinus, Blatela germanica, and Periplaneta americana from Phadia (AB, Uppsala Sweden).
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