Antibioclic—An Example of a Clinical Decision Support System for Antibiotic Prescribing

Antibioclic is a French CDSS for antibiotic prescribing in primary care, [27] targeting 37 common infectious diseases, freely available on the web and as a smartphone app on iOS and Android. It was codeveloped by general practitioners, specialists of infectious diseases, and engineers in 2011. Clinicians can enter the diagnosis of a patient on the website or app, they are then asked a few targeted questions (age group, comorbidities, renal function, breastfeeding, and pregnancy). Finally, they receive a tailored recommendation of antibiotic regimen, dose, and duration according to French national guidelines. Multimedia Appendices 1 and 2 describe how to use Antibioclic respectively with slides or video in English. Antibioclic was developed using a systematic method to transform clinical practice guidelines from the French National Authority for Health and the French Infectious Diseases Society (SPILF) into decision trees in Antibioclic. Antibioclic is updated frequently and modified as soon as a new guideline is published. The number of Antibioclic users in France has steadily increased over the past years from a median (IQR) of 414 (245-494) a day in 2012 to 5365 (2891-5769) a day in 2018, without any saturation to date (Multimedia Appendix 3). The smartphone app has been downloaded 22,970 times on Android and 15,200 times on iOS. More details are described in a recent study [27].