The expression levels of six m6A RNA methylation regulators between tumor and normal tissues were compared using the t-test. The expression pattern of m6A RNA methylation regulators in COAD samples was denoted by the Pearson correlation matrix, and a correlation coefficient (r) was calculated. We plotted the ROC curve and calculated the area under the curve (AUC) to estimate the discrimination ability. The m6A RNA methylation regulators and clinicopathological features were analyzed using the t-test or one-way ANOVA.
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